Los Angeles Rams vs Philadelphia Eagles prediction: 3 of 3 AI models back Los Angeles Rams

Game outlook

The Rams are the better side in the exact version of this matchup that will take the field Sunday. Philadelphia is coming off a 27-7 Monday-night loss in Chicago and has only five days to reset before facing the league's most productive yardage offense. More importantly, the Eagles will be without WR DeVonta Smith, TE Dallas Goedert, WR Hollywood Brown, LG Landon Dickerson, LB Zack Baun and S Marcus Epps. That is not a normal injury list: it removes Hurts' leading target, his primary tight-end outlet, a major interior-line stabilizer, the defense's top linebacker, and a starting safety.

Los Angeles has its own meaningful absences — Aaron Donald and CB Jaylen Watson are out, and its tight-end depth is compromised — but the matchup is asymmetrical. Donald's absence should help Philadelphia's run game, yet the Eagles have not consistently created favorable downs: their offense has the league's worst three-and-out rate since 2025, and its short-yardage/early-down efficiency has remained a problem this season. The Rams have allowed 80 or fewer rushing yards in each of their last two games, while Philadelphia now has to manufacture offense without Smith, Goedert and Dickerson. That puts too much of the offense on Jalen Hurts, A.J. Brown and Saquon Barkley against a defense allowing only 5.1 passing yards per attempt through three games.

What decides it

> Philadelphia's depleted middle-of-the-field defense against the Rams' personnel flexibility is the swing factor.